De-UTI® Mannose

D-Mannose is a monosaccharide with a chemical structure similar to glucose. It is widely found in nature. It is a naturally occurring monosaccharide and can be found in various animals, plants, and microorganisms. The high-quality De-UTI® mannose is produced by high performance liquid chromatography. The high-pressure infusion pump, high-sensitivity detector and high-efficiency particle stationary phase are used to separate, qualitatively and quantitatively analyze the components in the liquid mixture.

Research indicates that consuming D-Mannose provides significant help in preventing urinary tract infection (UTI), can improve clinical symptoms, and extend the interval between UTIs, thereby reducing the need for antibiotics. Its mechanism is to prevent bacterial and fungal adhesion to the urethra, which results in infection [1][2][3]. In addition to that, D-mannose is a type of monosaccharide, which is difficult to metabolize in human body. Its absorption rate is eight times slower than that of glucose, so it is unlikely to enter carbohydrate metabolism when taken orally. About 90% of the consumed D-mannose will be excreted from the body. During this period, the level of blood sugar will not significantly increase, so that D-Mannose will not interrupt normal blood regulation. In addition, D-Mannose has already been proven to have characteristics of prebiotics [4]

High Quality De-UTI® mannose is used widely as a dietary supplement to support Urinary Tract Health (UTI). Diabetes can also be eaten because blood sugar will not increase significantly. Due to its moisturizing, anti-ageing and anti-inflammatory effects, it is used in personal care and cosmetic applications.

[1] Kranjčec, B., Papeš, D., Altarac S. (2014) D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial. World J Urol. 32(1):79-84.
[2] Porru, D., Parmigiani, A., Tinelli, C., et al. (2014) Oral D-mannose in recurrent urinary tract infections in women: a pilot study. Journal of Clinical Urology, Vol. 7(3) 208-213.
[3] Domenici, L., Monti, M., Bracchi, C., et al. (2016) D-mannose: a promising support for acute urinary tract infections in women. A pilot study. Eur Rev Med Pharmacol Sci. 20(13):2920-5.
[4] Korneeva, O.S., Cheremushkina, I.V., Glushchenko, A.S., et al. (2012) Prebiotic properties of mannose and its effect on specific resistance. Zh Mikrobiol Epidemiol Immunobiol. (5):67-70.